Electrophysiology of Unconventional Channels and Pores (Hardcover)

Electrophysiology of Unconventional Channels and Pores Cover Image
By Anne H. Delcour (Editor)
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This book examines the channels and pores that belong to an eclectic and ubiquitous class of unconventionaland arguably, sometimes strangepore-forming molecules, which fulfill fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores and may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions; for others, it consists of folded polypeptides. Some are released by cells in a soluble form that can pass through biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by virtue of its focus on a few or even a single unit, has provided invaluable insights into the mechanisms and structure-function relationships of these remarkable membrane entities. The respective chapters of this book highlight a representative set of these interesting investigations.

Product Details
ISBN: 9783319201481
ISBN-10: 3319201484
Publisher: Springer
Publication Date: November 3rd, 2015
Pages: 385
Language: English
Series: Springer Series in Biophysics